Bladder cancer due to

Described in two main categories, namely, chemical carcinogens and endogenous tryptophan metabolism.

① chemical carcinogens: pure amine-based non-carcinogenic effect of the substance is carcinogenic dye intermediates, such as in the l-naphthylamine, 2 - naphthylamine and joint-based amines, rubber and plastic Antioxidant 4 - Amino-Union Base also has the role of bladder cancer, people with cancer after the cancer mass contact with an incubation period of 5 to 50 years, more than 20 years.

② endogenous tryptophan metabolism and bladder cancer relationship, many of bladder cancer no clear history of exposure to chemical carcinogens quality may be related to the body of tryptophan metabolism abnormalities. Tryptophan accumulation of normal metabolites, the intermediate metabolites are o-hydroxy-amino phenolic substances and can cause bladder tumors in mice.

In recent years, smoking and bladder cancer found a clear relationship between smokers than non-smoking men in a high incidence of bladder cancer four times; artificially sweetened products such as saccharin are urinary bladder carcinogenic effect, another long-term use analgesic phenacetin can also increase the incidence of bladder cancer risk. Chronic bladder infection and stimulation as well as drug cyclophosphamide can also cause bladder cancer.