Radiotherapy colorectal

The past 50 years, despite the rapid development of surgical technology, but the cure rate of colorectal cancer surgery, five-year survival rate has remained at around 50%, treatment failure due mainly to a higher rate of local recurrence and therefore improve the treatment of colorectal cancer must be consider the comprehensive treatment. More present study, the effect is better integrated surgical and radiation treatment, including preoperative radiotherapy, intraoperative radiation, postoperative radiation, "sandwich" radiotherapy, all kinds of different combinations of treatment has its own different characteristics. With advanced rectal cancer, in particular, local tumor infiltration into nearby tissue (rectum next to the anterior tissue, peritoneal lymph nodes, bladder, urethra, pubic bone sticks) as well as in patients with surgical contraindications, application of palliative radiotherapy is also often a more satisfactory results.

Comprehensive radiotherapy and surgical treatment:

1. Preoperative radiotherapy

(1) increase the rate of surgical resection

(2) reduce the rate of lymph node invasion and the percentage of patients with advanced

(3) reduction of distant metastasis.

(4) reducing the local recurrence rate and increase the survival rate

2. Postoperative Radiotherapy

(1) reducing the rate of local recurrence: postoperative radiotherapy for patients to start very early, the effect will be better.

(2) increase the survival rate: 5-year survival rate of patients with postoperative radiotherapy compared with surgery alone had significantly improved.

3. "Sandwich" type of radiation therapy

In order to give full play to preoperative radiotherapy and postoperative radiation advantages and overcome the deficiencies of both, using preoperative radiotherapy - surgery - postoperative radiotherapy approach, called "sandwich" approach.

4. Intraoperative radiation

In order to improve tumor dose and reduce the unnecessary normal tissue irradiation, has been reported in recent years, under direct vision using intraoperative radiotherapy.

Radiotherapy alone:

1. Intracavitary radiation

Select the appropriate lesions and early cancer local control rate of up to 96%.

2. Simple external radiation

For locally advanced tumors, for various reasons, can not be surgery and postoperative recurrence of patients, application of external irradiation can relieve symptoms and relieve suffering. Sometimes patients can not be surgery, after radiation treatment, making surgery possible.

To further improve the treatment of colorectal cancer effects, a number of ongoing exploration of new treatments, new clinical application of neutron rays date value being further exploration.