2009年9月18日星期五

Treatment of liver cancer "three magic weapons" and "new weapons"

Liver tumors in general can be divided into two major categories of benign and malignant. Rare benign liver tumors, there is a common hepatic cavernous hemangioma and hepatic cyst. Liver cancer include liver cancer and other malignancies. The following introduces a common liver cancer treatment.

(A) in the treatment of liver cancer "three magic weapons"

Surgery, radiotherapy and chemotherapy is a cancer of the "three magic weapons", is the most common and most important of liver cancer treatment.

1. Surgical treatment

To date, surgical resection, including liver cancer is still the most common malignant tumors, including the most effective methods of treatment are at present the majority of cancer patients the main way to get cured. Because liver cancer was found there had been late, or because of cirrhosis can not tolerate surgery, the removal percentage was not high, so early advocate of prevention, early detection and early treatment. With early detection and treatment of liver cancer research at Moffitt, diagnostic standards and technology continues to improve, liver cancer in the early, asymptomatic stages can be found, enabling a growing number of early stage liver cancer patients have the opportunity to practice surgery the results would be improved significantly. Fudan University, Institute for the governance of liver cancer liver cancer patients in more than 400 cases have already survived more than 5 years, 120 cases of more than 10 years, the longest survival of up to 40 years.

2. Radiation Therapy

Radiation therapy is the use of radiation directly to tumor cells of anti-disease treatment. In the past, radiation therapy is non-surgical treatment of choice for liver cancer In recent years, interventional radiology, and other due to the development of topical treatments for slightly less.

Radiation therapy for unresectable liver tumors not suitable for or unwilling to intervene in the implementation of radiation therapy. Clinical practice in recent years found that radiation therapy and radiation combined with interventional therapy can significantly improve the efficacy of radiation therapy. In addition, local recurrence, lymph node metastasis and adrenal metastasis to radiation therapy available to better results. Radiotherapy with surgery, chemotherapy, immunization, medicine and other treatment methods in combination, will help to further improve the curative effect.

3. Interventional chemotherapy and radiation therapy

Chemotherapy that is applied chemistry drug treatment. Over the past half a century in the great, chemotherapy chemotherapy drugs from the past few single application development into a wide variety of drugs in combination. In addition to the original method of intravenous administration of systemic chemotherapy, but also appeared adjuvant chemotherapy, neoadjuvant chemotherapy, special means of chemotherapy (arteries, body cavity perfusion, etc.) and other new ways. Because chemotherapy drugs in the eradication of cancer cells at the same time will cause damage to the body of patients, at present do not advocate the clinical application of hepatocellular carcinoma patients with systemic intravenous chemotherapy, smaller radiation damage taken by interventional treatment.

Radiation treatment is developed in recent years new avenues of chemotherapy. The method is catheter into the liver through the hepatic artery blood supply, the injection of chemotherapy drugs, the advancement of local drug concentration in order to improve the efficacy of chemotherapy drugs while reducing the toxic side effects of other parts of the body.

Radiology interventional therapy is mainly applied situation is not too bad for patients with inoperable liver cancer. At present, this method has become unresectable primary liver cancer patients with non-surgical therapy of choice. The disadvantage is that, for secondary liver cancer and some primary liver cancer ineffective and can cause liver dysfunction.

(B) in the treatment of liver cancer "new weapon"

1. Topical treatment mainly referring to some of the B ultrasound-guided intratumoral puncture treatment, the principle is through physical, chemical, or radioactive damage to the tumor tissue necrosis, thus controlling and even curing purposes. Currently used clinically localized treatment methods include: ultrasound-guided puncture intratumoral injection of ethanol, acetic acid, etc.; percutaneous microwave coagulation therapy within the tumor, laser therapy; radiofrequency ablation, high-temperature high-temperature saline injection therapy; liquid nitrogen freezing; argon-helium cryoablation; high-intensity focused ultrasound.

2. Biological treatment of cancer biological therapy, following surgery, chemotherapy and radiotherapy after the fourth mode of cancer treatment. Biological treatment is mainly through the body's defense mechanism or biological response modifier's role to regulate the body's own biological response, thus inhibiting the growth of tumor treatment. At present, the main elements of biological treatment of immune therapy has been extended to immune therapy, directed therapy, induce differentiation therapy and gene therapy and other areas.

In short, the treatment of liver cancer is still surgery-based, integrated treatment model. Combined treatment is not a method as possible, but should be under different circumstances, both the overall and partial, identify priorities to be selected in order to achieve complementary effects. Undue, excessive and indiscriminate use of various methods and drugs, and sometimes counterproductive.

没有评论:

发表评论