In recent decades, the treatment of gynecological carcinoma has made considerable progress, but the efficacy of ovarian cancer except the there is no significant improvement. The incidence of ovarian cancer ranks third in gynecologic oncology, but the fatality rate was as the first. The cause of its high fatality rate is due to the growth of ovarian cancer, hidden parts can not be directly seen in patients with early stage is still a lack of simple and practical diagnostic method. The majority (about 70% or more) have been newly diagnosed patients with pelvic and abdominal cavity metastasis. Is being done to surgery, radiotherapy, chemotherapy, immune therapy such as combination therapy with traditional Chinese medicine treatment of middle and late effects in patients is still poor, and difficult to avoid recurrence. The early diagnosis and treatment of ovarian cancer patients get the prognosis is quite different. With epithelial ovarian cancer, for example, according to statistics, the 5-year survival rate, Ⅰ a period of 80%, Ⅱ was 40%; and Ⅲ, Ⅳ and just below 5%. Can be seen early discovery, early diagnosis and treatment of ovarian cancer patients is vital event.
To enhance awareness of prevention of ovarian cancer, now common symptoms of ovarian cancer and diagnosis of the main points described below:
1). Onset age: Ovarian cancer can occur at any age, high incidence of stage 40 to 70 years old, 50-year-old pre-and post-menopausal middle-aged women are the most prevalent, but the girls under the age of 20 also occurred. Into old age the ovaries of women shrinking smaller, if the pelvic examination can still touch ovary or mass should be highly suspicious of this disease are. Pre-adolescents and young, girls, ovary have yet to develop mature ovarian anal search is often intangible, such as the increase could reach the ovaries or B-found in the annex to mass, should be suspicious of this disease.
2). Gastrointestinal upset: early in patients with initial symptoms are often manifested in the gastrointestinal tract. Almost all the patients because of abdominal distention, poor appetite, diet and medical treatment to reduce or apparent weight loss. If there ascites, abdominal distension will be more obvious, but also suffer from abdominal pain.
3). Abdominal Masses: Most patients with bladder filling in the morning when you wake up inadvertently touched the lower abdomen mass, if the tumor growing rapidly or there should be highly suspicious ascites-based disease. But when the tumor is small (less than or equal to 7 cm) itself is often intangible, must rely on B-ultrasound to find ovarian cancer should be aware of things there are those less than or equal to 5 cm. Anti-Cancer regular gynecological examination is necessary, such as the discovery of about 5 cm ovarian tumor required to perform periodic follow-up, close observation.
4). Menstrual changes: Approximately 1 / 2 ovarian cancer patients abnormal menstruation, irregular vaginal bleeding. Clinical also found that ovarian dysfunction, such as delayed menarche, early menopause; dysmenorrhea, single, non-sterile or have a family history of ovarian cancer populations susceptible to the disease.
5). Compression symptoms: a large pelvic tumor compression symptoms often appear obvious and have frequent urination, then anxious, anal choke blocking, lower abdominal bulge or discomfort such as poor stool. Ovarian cancer occurs when the transfer of extensive pelvic and abdominal cavity and a large number of ascites, the oppression of symptoms were more common.
6). Gynecological examination: If the patient was found inside the swollen material Annex hard, uneven surface, poor activity should be highly suspicious of ovarian cancer were invasive adhesions. If the hit of about 5 cm in favor of solid tumor not to be missed.
7). B super-see: Substantive about 70% of ovarian tumor malignant; mixed cystic and solid tumors are mostly malignant. B-ultrasonic examination, if found to tumor thickness (the thickness of solid reflection more than 2 centimeters) should be highly suspicious malignant. CT examination, magnetic resonance imaging (MRI) examination can be aided diagnosis.
8). Other tests: posterior fornix puncture fluid and chest, ascites cytology diagnosis of help. CA125 detection of mainly epithelial ovarian tumors, alpha-fetoprotein (AFP) internal endodermal sinus tumor, choriocarcinoma, human chorionic gonadotropin for the diagnosis and prognosis of important reference value.
At present, laparotomy is still the primary means of disease diagnosis; and where feasible, surgical treatment is the most important choice for ovarian cancer treatment. After surgery can not only clear pathological types of ovarian tumors, lesions range, but can in a short time all or most of the tumor removed. Cases of early surgical options available to cure properly. Right middle and late cases of cytoreductive surgery for the upcoming abdominal pelvic cavity where the tumor can be removed therefore correspondingly cut will help the body anti-tumor capabilities, and for chemotherapy, radiotherapy and immunotherapy in the creation of an enabling environment, and improve the life quality, and improve the prognosis of great benefit.
2009年9月8日星期二
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